Modeling force-induced bio-polymer unfolding
نویسندگان
چکیده
منابع مشابه
Modeling force-induced bio-polymer unfolding
We study the conformations of polymer chains in a poor solvent, with and without bending rigidity, by means of a simple statistical mechanics model. This model can be exactly solved for chains of length up to N = 55 using exact enumeration techniques. We analyze in details the differences between the constant force and constant distance ensembles for large but finite N . At low temperatures, an...
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Native structures of wild-type proteins may unfold as external conditions change. Usually unfolding occurs as a result of raising temperature, increasing the concentration of denaturants such as urea or guanidinium chloride, or changing pH. Only recently it has been recognized that certain wild-type proteins are subject to external force and in the course of performing biological functions they...
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ژورنال
عنوان ژورنال: Journal of Mathematical Chemistry
سال: 2008
ISSN: 0259-9791,1572-8897
DOI: 10.1007/s10910-008-9377-4